2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
CAS: 77544-60-6
Molecular Formula: C15H24O7S
2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol - Names and Identifiers
2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol - Physico-chemical Properties
| Molecular Formula | C15H24O7S |
| Molar Mass | 348.41 |
| Density | 1.202 g/mL at 25 °C |
| Boling Point | 492.5±40.0 °C(Predicted) |
| Flash Point | >110℃ |
| pKa | 14.36±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D1.507 |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol - Risk and Safety
| Risk Codes | R25 - Toxic if swallowed R34 - Causes burns R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2927 8(6.1) / PGII |
| WGK Germany | 3 |
2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol - Upstream Downstream Industry
| Downstream Products | S-Acetyl-PEG3-Azido 1-mercapto-11-hydroxy-3,6,9-trioxaundecane Acetic acid, [2-[2-(2-aminoethoxy)ethoxy]ethoxy]- O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL H2N-PEG4-tBu |
2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol - Reference Information
| biological activity | Tetraethylene glycol monotosylate is a degradable (cleavable) acylhydrazone-based ADC linker used to synthesize antibody-coupled drugs (ADCs). Tetraethylene glycol monotosylate can also be used as Linker of PROTAC and can be used for synthesis of PROTAC. |
| target | Cleavable PEGs |
| in vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-10 22:29:15
2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol - Uses and synthesis methods
biological activity
Tetraethylene glycol monotosylate is a degradable (cleavable) acylhydrazone-based ADC linker used to synthesize antibody-coupled drugs (ADCs). Tetraethylene glycol monotosylate can also be used as Linker of PROTAC and can be used for synthesis of PROTAC.
target
Cleavable
PEGs
in vitro study
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Last Update：2024-04-10 22:29:15
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CAS: 77544-60-6
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Product Name: 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Visit Supplier Webpage Request for quotation
CAS: 77544-60-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 77544-60-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Downstream Products for 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
S-Acetyl-PEG3-Azido
1-mercapto-11-hydroxy-3,6,9-trioxaundecane
Acetic acid, [2-[2-(2-aminoethoxy)ethoxy]ethoxy]-
O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL
H2N-PEG4-tBu
1-mercapto-11-hydroxy-3,6,9-trioxaundecane
Acetic acid, [2-[2-(2-aminoethoxy)ethoxy]ethoxy]-
O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL
H2N-PEG4-tBu